{"id":14141,"date":"2017-06-13T10:39:51","date_gmt":"2017-06-13T08:39:51","guid":{"rendered":"https:\/\/reproduccionbilbao.es\/?p=9253"},"modified":"2026-04-15T11:57:04","modified_gmt":"2026-04-15T11:57:04","slug":"asisted-hatching","status":"publish","type":"post","link":"https:\/\/reproduccionbilbao.es\/fr\/asisted-hatching\/","title":{"rendered":"ASISTED HATCHING"},"content":{"rendered":"

[vc_row][vc_column][vc_column_text]<\/p>\n

Por Edurne Mart\u00ednez<\/a><\/u><\/strong><\/p>\n

\u00bfQue es?<\/strong><\/p>\n

Los ovocitos est\u00e1n recubiertos por una capa de glicoproteinas que hace las veces de cubierta protectora. Esta capa se llamada zona pel\u00facida (ZP), cumple una funci\u00f3n vital durante la fecundaci\u00f3n ya que el correcto reconocimiento y adhesi\u00f3n de los espermatozoides a la ZP es el paso previo a la entrada del espermatozoide. Durante los primeros d\u00edas del desarrollo embrionario el grosor de la zona pel\u00facida se mantiene constante, pero cuando llega a estadio de blastocisto, la ZP comienza a adelgazar. Este adelgazamiento progresivo se produce por la acci\u00f3n mec\u00e1nica y enzim\u00e1tica del embri\u00f3n. Finalmente, el embri\u00f3n ha de liberarse de esta ZP para poder implantarse en el endometrio.<\/p>\n

El \u201casisted hatching\u201d (AH) o en su traducci\u00f3n al castellano, eclosi\u00f3n asistida, consiste en perforar la ZP para ayudar al embri\u00f3n a salir, sin que este tenga que hacer grandes esfuerzos por liberarse.<\/p>\n

\u00bfComo se hace?<\/strong><\/p>\n

Existen varias formas de hacer AH. Puede hacerse con ayuda de \u00e1cido tirodes a baja concentraci\u00f3n; con ayuda de una pipeta se expone una peque\u00f1a franja de la ZP a la acci\u00f3n del \u00e1cido hasta que esta queda perforada, es una t\u00e9cnica que requiere cierta pericia, ya que una exposici\u00f3n prolongada al \u00e1cido podr\u00eda da\u00f1ar al embri\u00f3n.<\/p>\n

Tambi\u00e9n puede hacerse mediante la acci\u00f3n mec\u00e1nica de una pipeta, esta t\u00e9cnica conocida como \u201cdrilling\u201d, consiste en pellizcar la ZP por un extremo y llevarla hasta el otro extremo.<\/p>\n

Sin embargo, la manera m\u00e1s segura y r\u00e1pida de hacer un AH es hacerlo mediante la acci\u00f3n de un l\u00e1ser. Sin necesidad de mover al embri\u00f3n de su placa de cultivo, se coloca sobre el microscopio y se delimita la zona a perforar con un vector. Para evitar un posible sobrecalentamiento de la zona se utiliza un l\u00e1ser cuya intensidad sea regulable.<\/p>\n

[\/vc_column_text][vc_row_inner][vc_column_inner width=\u00a0\u00bb1\/2″][vc_single_image image=\u00a0\u00bb9254″ img_size=\u00a0\u00bbfull\u00a0\u00bb][\/vc_column_inner][vc_column_inner width=\u00a0\u00bb1\/2″][vc_single_image image=\u00a0\u00bb9255″ img_size=\u00a0\u00bbfull\u00a0\u00bb][\/vc_column_inner][\/vc_row_inner][vc_column_text]<\/p>\n

\u00bfCu\u00e1ndo debe hacerse?<\/strong><\/p>\n

Algunos procesos como la vitrificaci\u00f3n pueden producir un endurecimiento de la ZP. Es por eso que en Reproducci\u00f3n Bilbao despu\u00e9s de desvitrificar, si el embri\u00f3n no ha roto la zona por sus propios medios hacemos AH mediante la ayuda de un l\u00e1ser. De este modo el embri\u00f3n no gasta energ\u00eda intentando liberarse de la zona.<\/p>\n

Otros tratamientos como los diagn\u00f3sticos preimplantacionales ya implican AH para poder realizar la biopsia, por lo que en esos casos el embri\u00f3n se librar\u00e1 de la ZP con mayor facilidad.<\/p>\n

[\/vc_column_text][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"

[vc_row][vc_column][vc_column_text] Por Edurne Mart\u00ednez \u00bfQue es? Los ovocitos est\u00e1n recubiertos por una capa de glicoproteinas que hace las veces de cubierta protectora. Esta capa se llamada zona pel\u00facida (ZP), cumple una funci\u00f3n vital durante la fecundaci\u00f3n ya que el correcto reconocimiento y adhesi\u00f3n de los espermatozoides a la ZP es el paso previo a la <\/p>\n

right-arrow<\/title><\/path><\/svg>Read More \u00ab\u00a0ASISTED HATCHING\u00a0\u00bb<\/span>right-arrow<\/title><\/path><\/svg><\/a><\/div>\n","protected":false},"author":5,"featured_media":9254,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[48],"tags":[],"class_list":["post-14141","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-articulos"],"yoast_head":"\nASISTED HATCHING - Reproducci\u00f3n Bilbao<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/reproduccionbilbao.es\/asisted-hatching\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"ASISTED HATCHING - Reproducci\u00f3n Bilbao\" \/>\n<meta property=\"og:description\" content=\"[vc_row][vc_column][vc_column_text] Por Edurne Mart\u00ednez \u00bfQue es? Los ovocitos est\u00e1n recubiertos por una capa de glicoproteinas que hace las veces de cubierta protectora. Esta capa se llamada zona pel\u00facida (ZP), cumple una funci\u00f3n vital durante la fecundaci\u00f3n ya que el correcto reconocimiento y adhesi\u00f3n de los espermatozoides a la ZP es el paso previo a la right-arrowRead More "ASISTED HATCHING"right-arrow\" \/>\n<meta property=\"og:url\" content=\"https:\/\/reproduccionbilbao.es\/asisted-hatching\/\" \/>\n<meta property=\"og:site_name\" content=\"Reproducci\u00f3n Bilbao\" \/>\n<meta property=\"article:published_time\" content=\"2017-06-13T08:39:51+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2026-04-15T11:57:04+00:00\" \/>\n<meta name=\"author\" content=\"Edurne Martinez\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"\u00c9crit par\" \/>\n\t<meta name=\"twitter:data1\" content=\"Edurne Martinez\" \/>\n\t<meta name=\"twitter:label2\" content=\"Dur\u00e9e de lecture estim\u00e9e\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/reproduccionbilbao.es\\\/asisted-hatching\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/reproduccionbilbao.es\\\/asisted-hatching\\\/\"},\"author\":{\"name\":\"Edurne Martinez\",\"@id\":\"https:\\\/\\\/reproduccionbilbao.es\\\/#\\\/schema\\\/person\\\/4ee1726c81bd33fd6cb287cdac909a76\"},\"headline\":\"ASISTED HATCHING\",\"datePublished\":\"2017-06-13T08:39:51+00:00\",\"dateModified\":\"2026-04-15T11:57:04+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/reproduccionbilbao.es\\\/asisted-hatching\\\/\"},\"wordCount\":485,\"publisher\":{\"@id\":\"https:\\\/\\\/reproduccionbilbao.es\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/reproduccionbilbao.es\\\/asisted-hatching\\\/#primaryimage\"},\"thumbnailUrl\":\"\",\"articleSection\":[\"Art\u00edculos\"],\"inLanguage\":\"fr-FR\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/reproduccionbilbao.es\\\/asisted-hatching\\\/\",\"url\":\"https:\\\/\\\/reproduccionbilbao.es\\\/asisted-hatching\\\/\",\"name\":\"ASISTED HATCHING - 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